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科学家宣布首次使灭绝动物物种复活，将恐狼重新引入世界。 基因工程公司 Colossal Biosciences 培育了三只恐狼，并将它们命名为罗慕路斯、雷穆斯和卡丽熙，以纪念 HBO 热播剧《权力的游戏》中著名的传奇生物。 然而，这种白毛狼曾经在北美和南美漫游，大约 12,000 年前消失，可能是由于它们的猎物消失。 该公司从化石遗骸中提取了 DNA，并将其与现存最接近的亲属灰狼的遗传密码相结合。 Colossal 首席执行官兼联合创始人本·拉姆在一份声明中表示：“我们的团队从一颗 13,000 年前的牙齿和一个 72,000 年前的头骨中提取了 DNA，并培育出了健康的恐狼幼崽。” 随后，研究小组利用体细胞核移植技术将高质量的细胞系克隆到供体卵细胞中，这需要从供体细胞中提取 DNA。 随后，胚胎被移植到代孕妈妈体内，代孕妈妈于 2024 年 10 月生下了三只健康的幼崽。狼崽正在美国一个占地 2,000 多英亩的安全广阔生态保护区内繁衍生息。
Scientists have announced the first de-extinction of an animal species, reintroducing the dire wolf back into the world.
Colossal Biosciences, a genetic engineering company, birthed three dire wolves, naming them Romulus, Remus and Khaleesi in honor of the legendary creature made famous from the HBO hit series Game of Thrones.
However, the white-coated wolf once roamed North and South America before vanishing around 12,000 years ago likely to the disappearance of their prey.
The company extracted DNA from fossilized remains, which was combined with the genetic code of a gray wolf, the closest living relative.
Colossal CEO and co-founder Ben Lamm said in a statement: ‘Our team took DNA from a 13,000-year-old tooth and a 72,000-year-old skull and made healthy dire wolf puppies.’
The team then cloned high-quality cell lines using somatic cell nuclear transfer into donor egg cells, which involves taking the DNA out of the cell from a donor – in this case a body cell.
The embryos were then transferred to a surrogate, which gave birth to the three healthy pups in October 2024.
The wolves are thriving on a more than 2,000-acre secure expansive ecological preserve in the US.
